Abstract: This paper estimates the Curie depth in Greenland area based on the global magnetic anomaly data by using the centroid method. For further analysis we introduce the latest heat flow data, crustal structure and ocean age, which helps to deepen the understanding of thermal structure in the studied area. When the magnetic body satisfies different distribution assumptions, the different theoretical formulas and correction factors for calculating the Curie depth are summarized. Among these distribution assumptions, we apply the fractal distribution assumption to the Greenland area. The result shows that the Curie depth （ h_\rmb ） in the studied area is within 40 km, with an average depth of about 20 km and an estimation error of about 2.7 km. Based on h_\rmb , we calculate the distance h_\rmm from topography to Curie depth and the distance h_\rmc from the top crystalline basement to Curie depth. Besides, we correct surface heat flow to obtain Q_\rms according to different crustal types. We find that Q_\rms is approximately inversely proportional to h_\rmm , which proves that the result is reasonable. Further analysis shows that h_\rmb in the studied area is generally shallower than Moho depth, while in part of the northern Greenland, h_\rmb is deeper than Moho. In the ocean, h_\rmc increases with the age of the ocean crust.