Abstract: Based on the new one-dimensional velocity model in Fujian and Taiwan strait region, we analyzed the applicability of this model used for Fujian seismic monitoring network by compared with the existing South China velocity model. Theoretical travel time comparison shows that small difference appeared within 100 km of the epicentral distance although the two velocity models seem obviously different. To some extent, this reflects the mean velocity of this region given by these two models are consistent. By choosing 18 man-made explosion events, we test the location results based on these two models. If without constrain on focal depth, location results by using the South China velocity model are slightly better than the new one-dimensional velocity model, but when we set focal depth as 0 km, precision of location results are much better for one-dimensional velocity new model. As for 19 natural earthquake events of Xianyou earthquake sequence, as a result of small velocity variation in horizontal dimension for South China region, earthquake location precision by using both models are quite close. The origin times of the events estimated by the new one-dimensional velocity model are usually 0.61 s ahead, which also result in the residuals of location error significantly higher than those by using the South China velocity model.